Diplomatic relations between Indonesia and the United States have a long and complex history, starting when Indonesia achieved independence in 1945. The two countries officially established diplomatic relations in 1950. Since then, this relationship has been characterized by various dynamics influenced by political, economic and social interests at the domestic and global levels. The beginning of these diplomatic relations was marked by US support for Indonesian independence, despite various challenges, including during the Cold War era. The United States sees Indonesia as a strategic country in the Southeast Asia region because of its important location and abundant natural resource potential. In 1965, after a military coup in Indonesia, relations between the two countries experienced a new phase under the leadership of General Suharto, who established closer ties with the US, especially in military and economic aspects. Throughout the 1970s and 1980s, America provided significant economic and military assistance to Indonesia. However, US foreign policy is also seen as controversial; international criticism emerged regarding human rights violations under the Suharto regime. However, relations remain close, with the US supporting Indonesia as a strategic partner through cooperation in various fields. Entering the reform era at the end of the 1990s, diplomatic relations began to experience changes. Social justice and human rights began to come into focus, with America criticizing repressive measures by the Indonesian government. On the other hand, Indonesia is trying to strengthen its image internationally as a more open, democratic country. After the September 11 2001 terror attacks, relations between Indonesia and the United States entered a new phase. Terrorism became a major issue, and the two countries began to cooperate more closely in the field of security. The United States provides support for security programs in Indonesia, including training assistance for security forces. In the following decades, especially under the administration of President Joko Widodo, bilateral relations were further strengthened through official visits and agreements in various sectors such as trade and investment, education, and climate change. President Obama’s visit to Indonesia in 2010 was an important moment, considering that Obama had lived in Jakarta as a child. Recent developments show an increase in economic cooperation, especially with the emergence of the Indo-Pacific initiative which emphasizes the importance of stability and economic growth in the region. Trade relations between the two countries have also increased, with Indonesia becoming one of the main trading partners for agricultural and manufactured products. Through a balanced and collaborative approach, Indonesia and the United States continue to strive to overcome challenges in the current global era, such as climate change, global health and regional security challenges. This dynamic and mutually beneficial relationship reflects the commitment of both countries to strengthen cooperation in various fields to achieve common goals for regional prosperity and stability in Southeast Asia.